Formulation Development, Characterization & Estimation of Acid Neutralization Capacity of Shankha Bhasma Tablets for the Treatment of Dyspepsia
نویسندگان
چکیده
Shankha Bhasma is a popular Ayurvedic formulation which is used in hyperacidity, indigestion, ulcerative dyspepsia and other acid peptic disorders. The dosage uniformity and patient compliance can be increased and adultration can be decreased in ayurvedic powders by formulating them into tablets. The aim of the present work is to develop and evaluate Shankha Bhasma tablets using starch and acacia as a binder. Shankha Bhasma was evaluated for calcium content by titrimetric analysis. The granules were prepared by wet granulation method and the flowability of granules was studied. The prepared tablets were evaluated for different parameters such as weight variation, thickness uniformity, hardness, friability, disintegration time and acid neutralizing capacity (ANC).
منابع مشابه
Formulation and In-vitro Characterization of Sustained Release Matrix Type Ocular Timolol Maleate Mini-Tablet
The purpose of this study was preparation and evaluation of sustained release matrix type ocular mini-tablets of timolol maleate, as a potential formulation for the treatment of Glaucoma. Following the initial studies on timolol maleate powder, it was formulated into ocular mini-tablets. The polymers investigated in this study included cellulose derivatives (HEC, CMC, EC) and Carbopol971P. Mann...
متن کاملFormulation and In-vitro Characterization of Sustained Release Matrix Type Ocular Timolol Maleate Mini-Tablet
The purpose of this study was preparation and evaluation of sustained release matrix type ocular mini-tablets of timolol maleate, as a potential formulation for the treatment of Glaucoma. Following the initial studies on timolol maleate powder, it was formulated into ocular mini-tablets. The polymers investigated in this study included cellulose derivatives (HEC, CMC, EC) and Carbopol971P. Mann...
متن کاملPreparation and In vitro Characterization of Alprazolam Extended- Release Tablets Using HPMC 4000cps
The main aim of this study was preparation and evaluation of extended - release system ofthe anxiolytic substance. Alprazolam is a short-acting benzodiazepine with general propertiessimilar to those of diazepam. Our studies focused on development of extended drug deliverysystem based on Hydroxy Propyl Methyl Cellulose (HPMC 4000cps) as retard agent andPolyvinylpyrrolidone (PVP k30) as binder us...
متن کاملDevelopment of lipid micromatrices based sustained release tablets of glipizide: suitability of stearic acid as release retardant
The objective of research was to explore the suitability of lipids like compritol 888 ATO and stearic acid as release retardant to develop sustained release (SR) tablets. The SR micromatrices of lipid (s) and glipizide were prepared (LM1- LM6) as intermediate product by fusion method and assessed for various pharmacotechnical properties. Micromatrices were formulated as SR tablets (F1-F6) by di...
متن کاملSynthesis, characterization and swelling behavior investigation of gelatin-g-Poly(Acrylic Acid-co-Itaconic Acid)
A novel pH-responsive superabsorbent hydrogel based on gelatin was prepared through crosslinking copolymerization of poly (acrylic acid) and poly (itaconic acid). The copolymerization conditions including monomers, initiator, gelatin and crosslinker concentration, reaction temperature, and neutralization percent were systematically optimized to achieve a hydrogel with swelling capacity as high ...
متن کامل